Dellaire Lab - Publications

Selected Publications

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	Supervised Trainees are underlined
2012

Andrin, C., D. McDonald, K.M. Attwood, A. Rodrigue, S. Ghosh, R. Mirzayans, J-Y. Masson, G. Dellaire, and M.J. Hendzel (2012) "A Requirement for polymerized actin in DNA double strand break repair." Nucleus 2012 3(4) (LINK) PDF
Kuang, Y-Q., N. Charette, J. Frazer, P.J. Holland, K.M. Attwood, G. Dellaire, D.J. Dupré. (2012) "Dopamine Receptor-Interacting Protein 78 Acts as a Molecular Chaperone for CCR5 Chemokine Receptor Signaling Complex Organization". PLos ONE 7(7): e40522 (LINK)

*Salsman, J., M. Jagannathan, P. Paladino, P.-K. Chan, G. Dellaire, B. Raught, and L. Frappier (2012) "Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response " Journal of Virology 86(2):806-20 (LINK) *Cover of JVI issue 86(4)

2011

Xavier, A.C., H. Edwards, A.A. Dombkowski, T.B. Balci, J.N. Berman, G. Dellaire, C. Xie, S.A. Buck, L.H. Matherly, Y. Ge, and J.W. Taub. (2011) "A unique role for GATA1 in Down Syndrome acute megakaryocytic leukemia biology and therapy" PLoS ONE 6(11): e27486. (LINK)

Bauer, D.C., K. Willadsen, F.A. Buske, K. LeCao, T.L. Bailey, G. Dellaire, and M. Bodén. (2011) "Sorting the nuclear proteome" Bioinformatics 27(13):i7-14 (LINK)

Corkery, D., G. Dellaire*, and J. Berman (2011) “Leukemia Xenotransplantation in Zebrafish - Chemotherapy Response Assay in vivo" British Journal of Haematology 153(6):786-789 * Joint corresponding author PDF

Supplementary Movies: K562 Cells (MOVIE 1) and NB4 Cells circulating in the zebrafish (MOVIE 2)

*Kepkay, R., K.M. Attwood, Y. Ziv, Y., Shiloh, and G. Dellaire (2011) “KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin.” Cell Cycle 10(2):308-322 PDF

*This article was also the subject of two News & Views articles: Hemmerich, 2011; Salomoni, 2011

Cann, K. and G. Dellaire (2011) “Heterochromatin and the DNA damage response: the need to relax” Biochem. Cell Biol. 89(1):45-60 PDF

Cann, K., S. Huang and G. Dellaire (2011) " Nuclear Subdomains in Cancer", book chapter In Advances in Nuclear Architecture, Eds. Adams and Freemont, Springer.
PDF

2010

Bodén M., G. Dellaire, K. Burrage, T.L. Bailey (2010) “A Bayesian network model of proteins' association with promyelocytic leukemia (PML) nuclear bodies.” J. Comput. Biol. 17(4):617-630 PDF

Cann, K. and G. Dellaire (2010) “The nucleolus as a biomarker in cancer: past and future” Can. J. Pathol. 2(1):30-34 PDF

2009

*Dellaire, G., R. Kepkay and D.P.Bazett-Jones (2009) "High resolution imaging of changes in the structure and spatial organization of chromatin, γ-H2A.X and the MRN complex within etoposide-induced DNA repair foci.". Cell Cycle. 8(22):3750-3769
*(Cover of Cell Cycle) PDF

This article was also subject of a News & Views article.

2007

Dellaire, G. and D.P.Bazett-Jones (2007) "Beyond Repair Foci: Subnuclear Domains and the Cellular Response to DNA Damage". Cell Cycle. 6(15):1864-1872. PDF

2006

Dellaire, G., R. Ching, K. Ahmed, K. Tse, F. Jalali, R.G. Bristow, and D.P. Bazett-Jones. (2006a) “PML nuclear bodies are DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1, Chk2 and ATR”.
J. Cell Biol. 175(1):55-66 PDF

Block, G., C.H. Eskiw, G. Dellaire, and D.P. Bazett-Jones.(2006) “Transcriptional regulation is affected by subnuclear targeting of reporter plasmids to PML nuclear bodies” Mol. Cell. Biol. 26(23):8814-8825 Pubmed

*Dellaire, G., R. Ching, H. Dehghani, Y. Ren and D.P. Bazett-Jones. (2006b) “ PML nuclear bodies increase in number in early S-phase by a fission mechanism”. J. Cell Sci. 119(6):1026-1033. (*article highlighted by JCS). PDF

*Dellaire, G., C. Eskiw, H. Dehghani, R. Ching, and D.P. Bazett-Jones. (2006c) “Mitotic Accumulations of PML protein (MAPPs) contribute to the post-mitotic re-establishment of PML nuclear bodies.” J. Cell Sci. 119(6):1034-1042. (*article highlighted by JCS). Pubmed

*Kruhlak, M.J., A. Celeste, G. Dellaire, O. Fernandez-Capetillo,W.G. Müller, J.G. McNally, D.P. Bazett-Jones, and A. Nussenzweig. (2006) “Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks” J. Cell Biol. 172(6):823-834 (*Highlighted by JCB, reviewed by the Faculty of 1000) Pubmed

2005

*Al Rashid, S.T., G. Dellaire, F. Jalali, M. Vaid, M. Folkard, Y. Xu, D.J. Chen,L. Lilge,K.M. Prise, D.P. Bazett-Jones, and R.G. Bristow. (2005) “Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks In vivo. “ Cancer Res. 65(23):10810-10821
*(Cover of Cancer Res.) Pubmed

Ching, R.W., G. Dellaire, C.H. Eskiw and D.P. Bazett-Jones (2005) “PML nuclear bodies: a meeting place for genomic loci?” J. Cell Sci. 118(5):847-854. Pubmed

Dehghani, H, G. Dellaire, and D.P. Bazett-Jones (2005) “Organisation of chromatin in the interphase mammalian cell”. Micron 36(2):95-108. Pubmed

2004

*Dellaire, G. and D.P. Bazett-Jones (2004) “PML nuclear bodies: Dynamic sensors of DNA damage and cellular stress”. Bioessays 26(9):963-977. *(Cover of Bioessays) PDF

Eskiw, C., G. Dellaire, and D.P. Bazett-Jones. (2004)“Chromatin contributes to structural integrity of PML bodies through a SUMO-1-independent mechanism”. J. Biol. Chem. 279(10):9577-9585. Pubmed

Dellaire, G., R. Nisman, and D.P. Bazett-Jones. (2004) "Correlative light and electron spectroscopic imaging of chromatin in situ." Methods in Ezymology, 375:456-478. PDF

2003

*Eskiw, C., G. Dellaire, J.S. Mymryck and D.P. Bazett-Jones. (2003)“Size, position and dynamic behaviour of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly”J. Cell Sci. 116(21): 4455-4466.
*(article highlighted by JCS, cover caption). Pubmed

Dellaire, G., R. Farrall, and W.A. Bickmore. (2003) “The Nuclear Protein Database (NPD): Subnuclear localization and functional annotation of the nuclear proteome”.* Nucl. Acids Res 31(1):328-330.
*(reviewed by Nat. Rev. Genet., J. Cell Sci. and Science) Pubmed		Visit NPD!

2002

*Collins, N., Garcia-Jimenez, N., I. Kukimoto, C. Garcia-Jimenez, G.Dellaire, and P. D. Varga-Weisz (2002) “ACF1 chromatin remodeling factor is essential for DNA replication in mammalian cells.” Nat. Genet. 32(4):627-632. *(highlighted by Nat. Genet., reviewed by the Faculty of 1000) Pubmed

Dellaire, G., E. M. Makarov, J.J. Cowger, D. Longman, H.G.E. Sutherland, R. Luhrmann, J. Torchia and W.A. Bickmore. (2002a) “Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes”. Mol. Cell. Biol. 22(14):5141-5156. Pubmed

*Dellaire, G., J. Yan, K. Little, R. Drouin and P. Chartrand. (2002b) “Evidence that extrachromosomal and chromosomal double-strand break repair are coupled in mammalian cells”. Chromosoma 111(5):304-312. *(Cover of Chromosoma) Pubmed

2001

Sutherland, H.G., Mumford, G.K., Newton, K., Ford, L.V., Farrall, R., Dellaire, G., Caceres, J.F., Bickmore, W.A. "Large-scale identification of mammalian proteins localized to nuclear sub-compartments." Hum Mol Genet. 2001 Sep 1;10(18):1995-2011. Pubmed

2000

Poot, R.A., Dellaire, G., Hulsmann, B.B., Grimaldi, M.A., Corona, D.F., Becker, P.B., Bickmore, W.A., and Varga-Weisz, P.D. (2000) "HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins." EMBO J. 2000 Jul 3;19(13):3377-3387. Pubmed